Health Condition 1: O021- Missed abortion
Conditions
Interventions
Intervention1: Misoprostol alone: Misoprostol 400mcg BD per vaginal for 1 day alone
Control Intervention1: Mifepristone, Misoprostol: Mifepristone
200 mg OD PO for 1 day
Misoprostol
400 mcg BD Per v
Sponsors
Sai Raja Nandini Kilari
Eligibility
Inclusion criteria
Inclusion criteria: Women with scan finding of missed miscarriage the criteria include any one of these: Intrauterine gestation with gestational sac - 20 mm with no evidence of an embryo/yolk sac. Intrauterine gestation with CRL-6 mm without cardiac activity. Intrauterine gestation with gestational sac -20 mm/CRL -6 mm with no growth in 7 days. Radiological signs of abnormal pregnancy—irregular sac/debris within the gestational sac. Conscious and co-operative patients. Patients willing to give consent.
Exclusion criteria
Exclusion criteria: Women who opted for alternative methods of miscarriage management (expectant or surgical). Women with Missed miscarriages in second trimester. Induced abortions. Diagnosis of Incomplete miscarriage. Hemodynamic instability. Life threatening bleeding. Contraindications to Mifepristone or Misoprostol. Patients not willing to give consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To investigate whether treatment with mifepristone plus vaginal misoprostol would result in a higher rate of successful medical management of missed miscarriage compared with vaginal misoprostol alone.Timepoint: 1 assessment after 24 hours 2 assessment after 48 hours | — |
Secondary
| Measure | Time frame |
|---|---|
| To assess the efficacy and safety of combination of Mifepristone and misoprostol Vs efficacy and safety of misoprostol alone. Timepoint: 1 assessment after 24 hours 2 assessment after 48 hours | — |
Countries
India
Contacts
Public ContactSai Raja Nandini Kilari
Dr MGR educational and research institute Deemed to be university
Outcome results
None listed