A study to compare the efficacy of 3-0 silk suture material versus N-butyl 2 cyanoacrylate glue in intra-oral soft tissue closure in alveoloplasty

Evaluation of efficacy of n-butyl 2 cyanoacrylate in intra-oral soft tissue closure in alveoloplasty: Clinical split-mouth comparative study - ALVBUT1

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/12/078045

Enrollment

Registered

2024-12-12

Start date

Unknown

Completion date

Unknown

Last updated

2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: - Health Condition 2: O- Medical and Surgical Health Condition 3: M858- Other specified disorders of bonedensity and structure

Interventions

Intervention1: N-BUTYL-2-CYANOACRYLATE GLUE (Truseal, Healthium, Medtech, India) : Truseal wound Closure device Topical Skin Adhesive N-BUTYL-2-CYANOACRYLATE 10 units 0.25ml Healthium Total duration:

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients of both genders aged between 30-70 years. 2. Patients indicated for alveoloplasty. 3. Patients non-allergic to cyanoacrylates and silk. 4. Patients willing for participation in the study and give written informed consent. 5. Patients indicated for alveoloplasty in both sides of either maxilla or mandible.

Exclusion criteria

Exclusion criteria: 1. Patients who are allergic to cyanoacrylates and silk. 2. Patients out of the age range of 30-70 years. 3. Patients with compromised systemic health - uncontrolled diabetes, severe cardiovascular diseases or immunocompromised patients 4. Patients on steroid therapy etc. 5. Inadequate bone volume, active infections, poor oral hygiene, haemorrhagic disorders, severe anxiety, psychological disorders. 6. Chronic smoking habit, pregnancy and recent radiation therapy.

Design outcomes

Primary

Measure	Time frame
Intra-operative ease of closure of the surgical site and efficient hemostasis with use of cyanoacrylate glue. Timepoint: Follow up: Clinical assessment will be performed at immediate post-operatively, 3rd, 7th, 14th and 21st days post-operatively.	—

Secondary

Measure	Time frame
Effective wound healing, lesser pain & no suture tracks evident on operative site, post-operatively, can be used as relevantly as conventional method of wound closure, that is, suturingTimepoint: Follow up: Clinical assessment will be performed at immediate post-operative 3rd, 7th, 14th & 21st days post-operatively.	—

Countries

India

Contacts

Public ContactDr Nilesh Mishra

Krishna Vishwa Vidyapeeth, Karad

nileshmishra1934@gmail.com9158542384

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026