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A clinical trial of study the effect of two drug(depot methylprednisolone and depot betamethasone) in lower back pain

Comparative study of epidural injection of depot methylprednisolone vs depot betamethasone in lower back pain - Nil

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/12/078017
Enrollment
90
Registered
2024-12-12
Start date
Unknown
Completion date
Unknown
Last updated
2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: - Health Condition 2: G64- Other disorders of peripheral nervous system

Interventions

Intervention1: 0.5% Bupivacaine, Depot Methylprednisolone, Depot Betamethasone: Dose - 2 Groups Group MP - Patient will receive 3 ml of 0.5% Bupivacaine plus 2ml (80mg) Depot Methylprednisolone plus

Sponsors

Department of Anaesthesia and Critical Care Hind Institute of Medical Sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patient choice not willing for spine surgeries sustain lumbar pain with nrs pain intentsity of score 5 or irresponsive to conservative treatment Reffered for ESI from orthopedic and neurosurgeons

Exclusion criteria

Exclusion criteria: patient refusal pregnancy uncontrolled diabetes steroid allergy spine deformities

Design outcomes

Primary

MeasureTime frame
Comparison of post-procedure analgesic effect in terms of Duration of analgesic effect, Peak Numerical Rating Scale pain scores during recovery period.Timepoint: Access the Numerical rating scale and Oswestry Disability Index score i.e. at baseline, post procedure at 5 min, 10 min, 15 min ,20 min ,25 min, 30 min, 1 hr, 2 hr, day 7, day 14, day 30, day 45, day 60, day 75, day 90 recorded.

Secondary

MeasureTime frame
Disability index scores, Adverse effects, if any.Timepoint: Numerical rating scale & Oswestry Disability Index at 5min,10min,15min,20min,25min,30min,1hour,2hour,day 7, day 14,day 30,day 45,day 60,day 75, day 90 after giving ESI If adverse effect nausea, vomiting,etc. if noted

Countries

India

Contacts

Public ContactShivani Yadav

Hind Institute of Medical Sciences

shamshir66@gmail.com9140448014

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026