Health Condition 1: N189- Chronic kidney disease, unspecified
Conditions
Interventions
Intervention1: monthly vitamin d: monthly vitamin D 60000iu every month for 6 months duration
Control Intervention1: daily vitamin D: Daily vitamin D supplementation 2000iu for 6 months duration
Sponsors
Pujitha Vallabhaneni
Eligibility
Inclusion criteria
Inclusion criteria: Age 1 to 14 years CKD with eGFR less than 60ml/1.73m2/hr Children with vitamin D levels between 12 to 50ng/ml Patient willing to give written informed consent
Exclusion criteria
Exclusion criteria: •Vitamin D levels of more than 100ng/ml or hypercalciuria or nephrocalcinosis or hypercalcemia, or suppressed iPTH •Not willing to come for follow-up at 3 months and 6 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Compare 25 hydroxy vitamin D levelsTimepoint: Baseline, 12 weeks, 24 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| Urine spot calcium creatinine ratio, USG KUB for nephrocalcinosisTimepoint: baseline, 24 weeks;Estimated GFRTimepoint: Baseline, 12week, 24 weeks;Level of BSALP TRACP-5b CTX – ITimepoint: Baseline, 24 week;Bone mineral density measured by DEXATimepoint: Baseline, 24 weeks;Level of serum calcium, phosphate, iPTHTimepoint: Baseline, 12 weeks, 24 weeks | — |
Countries
India
Contacts
Public ContactDr Lesa Dawman
PGIMER Chandigarh
Outcome results
None listed