Comparison Between Amniotic Chorion Membrane and Platelet Rich Fibrin as Barrier Membrane in the Management of Grade II Furcation defects - A Split Mouth Study

Comparative Evaluation of Amniotic Chorion Membrane and Platelet Rich Fibrin as Barrier Membrane in the Management of Grade II Furcation Defects - A Split Mouth Study - NIL

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/12/077924

Enrollment

Registered

2024-12-10

Start date

Unknown

Completion date

Unknown

Last updated

2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K055- Other periodontal diseases

Interventions

Intervention1: Amniotic Chorion Membrane: Access flap surgery with regenerative therapy using bone graft followed by Amniotic Chorion Membrane as a barrier membrane will be done in mandibular molar ha

Eligibility

Inclusion criteria

Inclusion criteria: Presence of bilateral buccal Grade II furcation defect in relation to mandibular molars Gingival margin coronal to or at the level of the roof of the furcation defects. Horizontal probing depth = 3 mm at the furcation sites Patients showing compliance with the maintenance program and follow recall appointments Patient consenting to be a part of the study

Exclusion criteria

Exclusion criteria: Medical problems that would contraindicate routine periodontal surgery Pregnant and Lactating women Patients with any history of systemic diseases/conditions e.g. uncontrolled Diabetes Mellitus, chronic Rheumatoid arthritis, steroid therapy, autoimmune diseases etc. Patient who have received a history of periodontal surgery within 6 months Patients on antibiotic therapy from past 1 month Patients who are smokers

Design outcomes

Primary

Measure	Time frame
1.To measure and compare the post treatment changes in Probing Pocket Depth (PPD) in horizontal plane at Grade II furcation tooth 2.To measure and compare the post treatment changes in Probing Pocket Depth (PPD) in vertical plane at Grade II furcation tooth Timepoint: 3 months,6 months & 9 months	—

Secondary

Measure	Time frame
1. To measure and compare the post treatment changes in Clinical Attachment Level (horizontal) at the Grade II furcation tooth 2. To measure and compare the post treatment changes in Clinical Attachment Level (vertical) at the Grade II furcation tooth 3. To measure and compare the post treatment changes in Plaque Index (PI) 4. To measure and compare the post treatment changes in Gingival Index (GI) 5. To assess the post treatment changes radiographically Timepoint: 3 months,6 months & 9 months	—

Measure

Time frame

1. To measure and compare the post treatment changes in Clinical Attachment Level (horizontal) at the Grade II furcation tooth 2. To measure and compare the post treatment changes in Clinical Attachment Level (vertical) at the Grade II furcation tooth 3. To measure and compare the post treatment changes in Plaque Index (PI) 4. To measure and compare the post treatment changes in Gingival Index (GI) 5. To assess the post treatment changes radiographically Timepoint: 3 months,6 months & 9 months

—

Countries

India

Contacts

Public ContactCol Dr Manish Mukherjee

Armed Forces Medical College

cd44_mmm@yahoo.co.in9837692014

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026