Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Dexmedetomidine: Group D - 30 patients will be given 0.5 microgram per kilogram of dexmedetomidine diluted up to 1 milliliter
with normal saline subcutaneously given with using 26 gauge
Sponsors
JLN medical college and hospital
Eligibility
Inclusion criteria
Inclusion criteria: -Age group between 20 and 70 years -Body weight 40 to 80 kg. - Patients belonging to ASA (American Society of anaesthesiologist) class-I and II. - Patients undergoing various infraumbilical surgeries
Exclusion criteria
Exclusion criteria: -Patient’s refusal and uncooperative patients. -Any known hypersensitivity or contraindication to bupivacaine , clonidine and Dexmedetomidine., - Local pathology at the site of injection or disability limiting the performance of spinal block. - History of convulsion, altered coagulation profile, bleeding disorder, pre-existing neurological deficit, surgeries in prone position , obstructive sleep apnea, thyroid disorder, known allergy to bupivacaine, dexmedetomidine, clonidine. -Patient with history of respiratory, cardiac, hepatic or renal disease (necessitating classification in ASA Class III or above). -Patients having a history of significant neurological, psychiatric, or neuromuscular disorders.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| duration of analgesiaTimepoint: Baseline to 60 minutes | — |
Secondary
| Measure | Time frame |
|---|---|
| -Onset and duration of sensory block. - Onset and duration of motor block. - The intraoperative hemodynamic variability ( haemodynamic parameters) - Postoperative Visual analog scale (VAS) score - Ramsay sedation scale - Total analgesia requirement in 24 hour -Adverse effects if anyTimepoint: 24 hours | — |
Countries
India
Contacts
Public ContactDr Veena Patodi
JLN medical college and hospital, Ajmer
Outcome results
None listed