Health Condition 1: N200- Calculus of kidney Health Condition 2: N200- Calculus of kidney
Conditions
Interventions
Intervention1: Injection Tranexamic acid: Injection tranexamic acid 1gm diluted in 100mlnormal saline at the time of induction
Single dose
Control Intervention1: Placebo(distilled water): Distilled wa
Sponsors
CMC Vellore
Eligibility
Inclusion criteria
Inclusion criteria: 1.Age 18 years or more 2.Baseline Hb more than 10g/dl. 3.patients undergoing percutaneous nephrolithotomy
Exclusion criteria
Exclusion criteria: 1. patients with known allergy to tranexamic acid 2. Patients on anti-platelets or anti coagulation therapies. 3 Patients with history of venous thrombosis or pulmonary embolism 4. Non ambulant patients 5. CAD with drug eluting stent required Dual antiplatelet agents 6. CKD with MDRD less than 30ml/min/1.73m2 7. Patient’s refusal 8. Diagnosed with mental condition that impair the patient’s ability to provide informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The occurance of blood transfusion in PCNLTimepoint: From surgery till discharge | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood loss, operative time, Success rate, intra operative hypotension requiring vasopressors, Need for secondary procedures, complications, readmissionsTimepoint: Intra op, immediate post op, after six months post op | — |
Countries
India
Contacts
Public ContactSachin Paul James
CMC Vellore
Outcome results
None listed