Comparison of Buffered and Non-Buffered Lidocaine for Tooth Extractions

COMPARISON OF BUFFERED AND NON-BUFFERED LIDOCAINE FOR THERAPEUTIC EXTRACTIONS: A SPLIT-MOUTH, DOUBLE-BLINDED, RANDOMIZED TRIAL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/12/077839

Enrollment

Registered

2024-12-09

Start date

Unknown

Completion date

Unknown

Last updated

2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K088- Other specified disorders of teethand supporting structures

Interventions

Intervention1: Local infiltration in patients requiring extractions for therapeutic purposes: After screening the patients for inclusion criteria, randomization will be used to assign the type lignoca

Eligibility

Inclusion criteria

Inclusion criteria: Patients who want therapeutic extractions for orthodontic purpose

Exclusion criteria

Exclusion criteria: Patients requiring extractions other than therapeutic purpose

Design outcomes

Primary

Measure	Time frame
1.Pain on injection 2.Onset of action Timepoint: 1.Pain on injection is seen immediately at time of deposition of lignocaine. 2.Onset of action is seen in seconds immediately after injecting lignocaine.	—

Secondary

Measure	Time frame
1. Quantity of local anesthetic required in ml 2. Subjective pain score at the time of extraction using VASTimepoint: At baseline	—

Countries

India

Contacts

Public ContactDr Vipul Jain

Subharti Dental College

sameerpandey14@gmail.com917999597901

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026