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to study the effect of an anaesthetic drug named Lignocaine in patients undergoing brain surgery involving opening of skull for management of pain during and after surgery.

Evaluation of lignocaine infusion for management of pain after supratentorial craniotomy - NIL

Status
Recruiting
Phases
Phase 3Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/12/077832
Enrollment
60
Registered
2024-12-09
Start date
Unknown
Completion date
Unknown
Last updated
2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: G060- Intracranial abscess and granuloma

Interventions

Intervention1: Evaluation of lignocaine infusion for management of pain after supratentorial craniotomy: Group A patients undergoing supratentorial craniotomy will be given intravenous Lignocaine bolu

Sponsors

Dayanand Medical College and Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Adult male and femalae patients undergoing supratentorial craniotomy under General Anesthesia, American Society of Anaesthesiologist(ASA) Class 1 and 2, Glasgow Coma Scale of 15.

Exclusion criteria

Exclusion criteria: 1. Patients having cardiac conduction abnormalities like atrio-ventricular block. 2. Patients with respiratory, hepatic or renal disease. 3. Patients on treatment with calcium channel blockers or beta-blockers. 4. Patients with altered sensorium. 5. Patients with a history of myopathy or substance abuse. 6. Patients who will be kept mechanically ventilated postoperatively. 7. Allergic to study drug. 8. Patient’s refusal.

Design outcomes

Primary

MeasureTime frame
Analgesic efficacy of IV lignocaine infusion as assessed by post operative pain score measured using Numeric rating scale (NRS).Timepoint: Analgesic efficacy of IV lignocaine infusion as assessed by post operative pain score measured using Numeric rating scale (NRS)measured after shifting the patients to post anaesthesia care unit at 0 hour, 1 hour, 2 hour and 3 hour.

Secondary

MeasureTime frame
1.Total opioid consumption in 24 hours from start of surgery 2.To observe for adverse effects, if any during surgery & within 24 hours of surgeryTimepoint: 1.Total opioid consumption till 24 hours after surgery 2.To observe for adverse effects within 24 hours of surgery

Countries

India

Contacts

Public ContactDr Supreen kaur

Dayanand Medical College and Hospital

supreenkaur0179@gmail.com8360285668

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026