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A follow-up study to evaluate the effectiveness of memantine as an add on treatment for cognitive symptoms in schizophrenia

Memantine as an adjuvant in cognitive symptoms of schizophrenia with chronic course a follow up study - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2024/12/077774
Enrollment
50
Registered
2024-12-06
Start date
Unknown
Completion date
Unknown
Last updated
2024-12-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: F20- Schizophrenia

Interventions

Intervention1: NIL: NIL Control Intervention1: NIL: NIL

Sponsors

mohammed Abdul Salaam
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients diagnosed with schizophrenia according to ICD 10 with a duration of illness more than two years, stable without active symptomatology and on anti psychotic treatment

Exclusion criteria

Exclusion criteria: Patients who are not given consent and who are on on any CNS drugs

Design outcomes

Primary

MeasureTime frame
To measure clinical utility of memantine effectiveness in schizophrenia patients along with second generation antipsychotics in ameliorating the cognitive symptoms of schizophreniaTimepoint: Baseline: The cognitive functions at baseline will be assessed using Addenbrooke’s cognitive examination (ACE) scale. Memantine will be added to the ongoing treatment as an adjunctive At the end of study: ACE scale will be repeated at the end of eight weeks.

Secondary

MeasureTime frame
Improvement in cognitive symptoms score through ACE scaleTimepoint: At the end of 8 weeks cognitive assessment is done using ACE scale

Countries

India

Contacts

Public ContactMohammed Abdul Salaam

Konaseema institute of medical sciences and research foundation

salaammd05@gmail.com9885320662

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026