Comparing effects of various adjuvants added to anaesthetic agent in patients undergoing lower limb surgery under a combination of Spinal Anaesthesia and lumbar and sacral plexus blocks

Status

Recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/12/077716

Enrollment

Registered

2024-12-05

Start date

Unknown

Completion date

Unknown

Last updated

2024-12-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: S72- Fracture of femur Health Condition 2: O- Medical and Surgical Health Condition 3: S729- Unspecified fracture of femur

Interventions

Intervention1: Adrenaline as adjuvant in Low dose spinal with lumbar and sacral plexus blocks: Safety, efficacy, haemodynamic effects and duration of effect Control Intervention1: Buprenorphine as adj

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients undergoing lower limb surgeries including trauma surgery 2. Age above 18

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
A Prospective Randomised Control trial to compare the Haemodynamic effects and duration of Anaesthesia of Adrenaline, Buprenorphine, and Dexmedetomidine, when used as adjuvants in in Low Dose Spinal Anaesthesia in combination with Lumbar and Sacral Plexus Blocks, for lower limb surgery.Timepoint: 15 minute interval during surgery and at 2 hourly intervals post operative, until analgesic is required, at which point the study is terminated	—

Measure

Time frame

A Prospective Randomised Control trial to compare the Haemodynamic effects and duration of Anaesthesia of Adrenaline, Buprenorphine, and Dexmedetomidine, when used as adjuvants in in Low Dose Spinal Anaesthesia in combination with Lumbar and Sacral Plexus Blocks, for lower limb surgery.Timepoint: 15 minute interval during surgery and at 2 hourly intervals post operative, until analgesic is required, at which point the study is terminated

—

Secondary

Measure	Time frame
NilTimepoint: Nil	—

Countries

India

Contacts

Public ContactDr Nikhil Karkhanis

Vikhe Patil Institute of Medical Sciences

nikhilkarkhanis@rediffmail.com09977000738

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026