Health Condition 1: M263- Anomalies of tooth position of fully erupted tooth or teeth Health Condition 2: K088- Other specified disorders of teethand supporting structures
Conditions
Interventions
Intervention1: IPRF on experimental side: Injection of IPRF once on the experimental side which will be deiced by randomization to be either right or left side after one month of placement of L-PRF an
Sponsors
AIIMS Bhubanswar
Eligibility
Inclusion criteria
Inclusion criteria: Subjects having Class I bimaxillary dentoalveolar protrusion malocclusion or Class II div 1 malocclusion with normodivergent growth pattern (FMA 20°- 28°), minimum spacing (2-5mm) or crowding in maxillary and mandibular arches, and require either all 1st premolars extraction or only upper 1st premolars extraction for the correction of their malocclusions. Presence of full complement of teeth except 3rd molars.
Exclusion criteria
Exclusion criteria: History of complete or incomplete comprehensive orthodontic treatment Subject who fails to maintain proper oral hygiene all through the orthodontic treatment Subjects with pregnancy Subjects having any known syndrome or metabolic disorder affecting calcium and phosphate metabolism Subjects on long-term medication like NSAID’S or steroids Lack of manual dexterity Any medications for systemic illness
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Addition of I-PRF will enhance the orthodontic tooth moventTimepoint: T0-Placement of L-PRF plug in extraction sockets and start of canine retractiion T1- 30 days T2- 45 days T3- 60 days T4- 75 days T- 90 days | — |
Secondary
| Measure | Time frame |
|---|---|
| Addition of I-PRF will enhance the release of various biomarkersTimepoint: T0-Placement of L-PRF plug in extraction sockets and start of canine retractiion T1- 30 days T2- 45 days T3- 60 days T4- 75 days T5- 90 days | — |
Countries
India
Contacts
Public ContactDamodar Bhat
AIIMS BHUBANESWAR
Outcome results
None listed