Health Condition 1: F20- Schizophrenia
Conditions
Interventions
Intervention1: Transcranial alternating current stimulation: A 4x1 montage will be used with 2 mA current being delivered at the central F3 location. The peripheral 4 electrodes will get 25% (0.5mA) c
Sponsors
National Institute of Mental Health and Neurosciences
Eligibility
Inclusion criteria
Inclusion criteria: Diagnosis of psychotic disorder as per International Classification of Diseases 10 at least as minimal sociooccupational dysfunction SOFAS more than 20. On a stable medication for the last 6 weeks with no major functionality in this 6 week period Providing written informed consent only patients with intact capacity to consent will be approached
Exclusion criteria
Exclusion criteria: Features suggestive of risk of harm to self (for example: suicidal risk, catatonia, prolonged nutritional deprivation) or others (for example: aggression or excitement) Need for Electroconvulsive therapy Recent history of antibiotic usage within the past 6 weeks Co-existing inflammatory bowel disease Co-morbid substance dependence (except caffeine and nicotine) Any significant medical or neurological disorder or condition affecting auditory, visual or any sensory modalities which remain uncorrected Any local skin lesion near the site of stimulation or any other contraindication to tACS.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Social and occupational functioningTimepoint: 6 week | — |
Secondary
| Measure | Time frame |
|---|---|
| heart rate variability markers electrogastrography markers Electroencephalography markers self-referential processing Psychopathology rating scoresTimepoint: change from before tACS to 2 days and 6 weeks after tACS | — |
Countries
India
Contacts
Public ContactDr. Sreeraj V S
National Institute of Mental Health and Neurosciences (NIMHANS)
Outcome results
None listed