Health Condition 1: N711- Chronic inflammatory disease of uterus Health Condition 2: N800- Endometriosis of uterus
Conditions
Interventions
Intervention1: Probiotic: Probiotic capsule containing 10 billion CFU of strains of Lactobacillus, Streptococcus and
Bifidobacterium for 12 weeks
Control Intervention1: Placebo: Microcrystalline Cellu
Sponsors
Gupte Hospital and Centre for Research in Reproduction
Eligibility
Inclusion criteria
Inclusion criteria: 1. Women aged 20-50 years with a confirmed diagnosis of endometriosis. 2. Experiencing moderate to severe endometriosis-related pain (e.g., dysmenorrhea, dyspareunia). 3. Complaints of gastrointestinal disturbances (e.g., bloating, IBS-like symptoms) related to endometriosis. 4. Stable hormonal therapy regimen for at least 3 months, if applicable.
Exclusion criteria
Exclusion criteria: 1. Subjects who are pregnant, have known allergies to resveratrol or contraindications to monophasic contraceptive pills, according to World Health Organization eligibility criteria. 2. Women on previous probiotic supplementation will be excluded from this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Reduction in the chronic pain and improved digestive function in women with endometriosis. 2. Effect on CA-125 a biomarker for endometriosisTimepoint: At baseline and after 12 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| Insights into the specific mechanisms by which probiotics exert their effects on endometriosis could lead to the development of more targeted and effective treatments.Timepoint: 12 months | — |
Countries
India
Contacts
Public ContactDr Preeti Arora
Research Division of Accurate Diagnostics Pvt. Ltd. Genomic Research and Solutions Pvt. Ltd.
Outcome results
None listed