Comparison between Hyperbaric Levobupivacaine with Hyperbaric Bupivacaine in spinal anesthesia along with fentanyl in patients undergoing -Total abdominal hysterectomy- A single Blind study

A Comparitive study of Hyperbaric Levobupivacaine with Hyperbaric Bupivacaine in spinal anesthesia with adjuvant fentanyl in patients undergoing -Total abdominal hysterectomy- A single Blinded study - NIL

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/12/077524

Enrollment

Registered

2024-12-02

Start date

Unknown

Completion date

Unknown

Last updated

2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Spinal Anaesthesia: Injection bupivacaine (3ml) and levobupivacain(3ml) with injection fentanyl(25cc) will be given intrathecaly for spinal anaesthesia in patients undergoing transabdom

Eligibility

Inclusion criteria

Inclusion criteria: 1-Patient aged 30 -65 yr. 2- ASA grade I, II. ?

Exclusion criteria

Exclusion criteria: 1-patient refusal 2-patients with coagulation disorders or on anticoagulants, spinal deformity, allergic to amide local anaesthetics, 4-Patients with musculoskeletal and psychiatric diseases that could make our technique difficult 5-surgeries lasting for more than 1.5hr.

Design outcomes

Primary

Measure	Time frame
To compare efficacy of 0.5% hyperbaric levobupivacaine and 0.5% hyperbaric bupivacaine with adjuvant fentanyl in terms of sensory and motor block in patients undergoing total abdominal hysterectomy. Timepoint: Onset of sensory block- recording every minute for first 10 min then every 5min will be done. Max height of sensory block (T5/6) will be recorded.	—

Secondary

Measure	Time frame
To compare the effect on change in hemodynamics parameter and side effects using these same drugs. Timepoint: After injecting the drug hemodynamic parameters (NIBP, Pulse Rate, Pulse Oxymetry) changes will be recorded every 5min till the end of the surgery	—

Countries

India

Contacts

Public ContactDr Kirti Pandey

Heritage Institute of Medical Sciences

pushkarranjanbhu@gmail.com9415986684

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026