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A Study to compare two doses of Dexmedetomidine as an additive in injection Ropivacaine for an analgesic abdominal block for hernia surgery

Comparison Of 0.25mcg/kg Dexmedetomidine and 0.5mcg/kg Dexmedetomidine as an Adjuvant to 0.2% Ropivacaine For Postoperative Analgesia in Ultrasound Guided Transversus Abdominis Plane Block for Open Inguinal Hernia Repair – A Randomized Controlled Trial - Nil

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/11/077503
Enrollment
68
Registered
2024-11-29
Start date
Unknown
Completion date
Unknown
Last updated
2024-12-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: 0.25mcg/kg Dexmedetomidine in 2ml NS and 18 ml of 0.2% Ropivacaine: Ultrasound Guided Transversus Abdominus Plane Block using 0.25mcg/kg Dexmedetomidine in 2ml NS and 18 ml of 0.2% Ropi

Sponsors

NKP Salve Institute of Medical Sciences and Research Centre and Lata Mangeshkar Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1) Patient scheduled for elective open Inguinal hernia surgery under subarachnoid block. 2) American society of Anesthesiologist (ASA) physical status I, II. 3) Patient giving consent for study. 5) BMI less than 30 kg/m2

Exclusion criteria

Exclusion criteria: 1) Bleeding disorders. 2) History of cardiac, renal, respiratory or hepatic disease. 3) Allergy to study drugs. 4) Patients consuming adrenoceptors agonist or antagonist.

Design outcomes

Primary

MeasureTime frame
Comparison of dexmedetomidine 0.25mcg/kg and 0.5 mcg/kg as an adjuvant to 0.2% ropivacaine for post operative analgesia in ultrasound guided transversus abdominis plane block in open inguinal hernia repairTimepoint: 1) Numerical rating scale (NRS) for pain assessment at 0,1,2,4,6,12 and 24 hours after surgery. 2) Time of requirement of first rescue analgesia in 24 hrs. 3) Total analgesic doses required in first 24 hours.

Secondary

MeasureTime frame
To compare side effects of dexmedetomidine 0.25mcg/kg and 0.5mcg/kg as an adjuvant to 0.2% ropivacaine in ultrasound guided transversus abdominis plane block in open inguinal hernia repair with respect to : 1) Sedation 2) Hemodynamic instabilityTimepoint: For 24 hrs after Surgery

Countries

India

Contacts

Public ContactDr Kalyani Thote

NKP salve institute of medical sciences and research centre and Lata Mangeshkar Hospital

anjali_bhure@yahoo.co.in9822563121

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026