Health Condition 1: K081- Complete loss of teeth
Conditions
Interventions
Intervention1: Soft tissue level implant: Endosseous implant insertion followed by restoration with screw retained crown after 3 months
Control Intervention1: Bone level implant: Bone level endosseous
Sponsors
Arvind R
Eligibility
Inclusion criteria
Inclusion criteria: Adult patients requiring implant insertion in premolar-molar region of right & left side of jaw located contiguous to natural teeth, tooth-bound edentulous space Healed implant sites with adequate osseous architecture, thick gingival biotype Absence of antibiotic therapy in the previous three months Nondiabetic (HbA1c less than 6.0 percent), Vit D more than 20ng per ml Signed informed consent and willing to come for follow up
Exclusion criteria
Exclusion criteria: Absence of keratinized tissue or need for crestal bone augmentation of implant site Diagnosis or History of periodontitis Systemic conditions contraindicating surgery, infectious diseases, medications influencing bone metabolism, immune modulators, previous pathologic conditions, bruxism, SSRI Pregnancy and lactation Smoking
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Marginal bone loss around soft tissue level and bone level implantsTimepoint: 6,12,18 months | — |
Secondary
| Measure | Time frame |
|---|---|
| Probing depth, Plaque Index and Bleeding on probing around soft tissue level and bone level implantsTimepoint: 6,12,18 months;Submucosal microbiota using real time PCR around soft tissue level and bone level implantsTimepoint: 6,18 months;Matrix metalloproteinase (MMP) in peri implant crevicular fluid around soft tissue level and bone level implantsTimepoint: 6, 18 months;Comparative metabolomics of peri implant crevicular fluid around soft tissue level and bone level implantsTimepoint: 6,18 months | — |
Countries
India
Contacts
Public ContactShobha J Rodrigues
Manipal College of Dental Sciences Mangalore Manipal Academy of Higher Education Manipal
Outcome results
None listed