To compare the efficacy of two drugs (local anaesthetics) during spinal anaesthesia

Comparison of intrathecal isobaric levobupivacaine versus hyperbaric levobupivacaine in lower abdominal surgeries - -

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/11/077467

Enrollment

Registered

2024-11-28

Start date

Unknown

Completion date

Unknown

Last updated

2024-12-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Comparison between isobaric and hyperbaric local anaesthetic drugs: Comparison of single shot intrathecal 0.5% isobaric levobupivacaine 3.5 ml versus single shot 0.5% hyperbaric levob

Eligibility

Inclusion criteria

Inclusion criteria: 1. ASA Grade I, II, III 2. Mallampatti Grading 1, 2 3. Patient giving valid informed consent 4. Lower abdominal surgeries

Exclusion criteria

Exclusion criteria: 1. ASA Grade IV 2. Mallampatti Grading 3, 4 3. Patient refusal 4. Patient with local infection at puncture site 5. Patient with ischaemic and rheumatic heart disease 6. Patient with coagulation defects and on anticoagulants 7. Patient allergic to local anaesthetic drugs

Design outcomes

Primary

Measure	Time frame
To compare the quality of sensory and motor blocks in terms of onset, time, total duration and maximum level attainmentTimepoint: From 0 minutes of administering spinal anaesthesia upto 60 minute postoperatively	—

Secondary

Measure	Time frame
To compare the effectiveness & hemodynamic stability between intrathecal isobaric levobupivacaine versus hyperbaric levobupivacaine in lower abdominal surgeriesTimepoint: From 0 minutes of administering spinal anaesthesia upto 60 minute postoperatively	—

Countries

India

Contacts

Public ContactDr P Brahmani

Vinayaka Missions Kirupananda Variyar Medical College and Hospitals

rasikamadhan1985@gmail.com8129340367

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026