Health Condition 1: N390- Urinary tract infection, site notspecified
Conditions
Interventions
Intervention1: Oral Lactobacillus: Patients shall be given oral lactobacillus therapy in the form of tablets thrice daily for 1 week followed once daily for 3 months.
Control Intervention1: Oral Antib
Sponsors
Aiims Bhubanesswar
Eligibility
Inclusion criteria
Inclusion criteria: Patients aged 18 years or above with culture-proven recurrent UTIs Written informed consent.
Exclusion criteria
Exclusion criteria: 1.Complicated cystitis 2.Uncomplicated pyelonephritis 3.A history of urologic abnormality or renal calculi 4.Recent sexually transmitted infections (STI) 5.History of recurrent Bacterial vaginosis 6.Risk factors for STI and human immunodeficiency virus (HIV) infection 7.Pregnancy or within 2 months of pregnancy 8.Lactation 9.Uncontrolled Diabetes (controlled would be enrolled) 10.Other immunocompromised states 11.Drug or alcohol abuse Abnormal pelvic examination results
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To see the rate of symptomatic UTIs (clinical recurrences (CR)) during the 3 months of therapy, as reported by the patientTimepoint: at presentation at 1 month at 3 months | — |
Secondary
| Measure | Time frame |
|---|---|
| a)To measure the number of microbiologically confirmed symptomatic UTIs (microbiologic recurrences) during the 3 months of prophylaxis.Timepoint: at presentation at 1 month at 3 months;b)To compare the time to the first Microbiologic Recurrence (MR). An MR was defined as a UTI based on the combination of clinical symptoms and bacteriuria (103 CFU/mL bacteria in midstream urine).Timepoint: at presentation at 1 month at 3 months;c)The most common causative microorganism in Indian women.Timepoint: at presentation at 1 month at 3 months | — |
Countries
India
Contacts
Public ContactDr Prasanna Ram
AIIMS
Outcome results
None listed