Comparison of effect of two different drugs under a single injection for patients coming for below knee surgeries and monitor postoperative pain relief for next 24 hours

Buprenorphine vs Clonidine as adjuvant for ultrasound guided popliteal sciatic nerve block in lower limb surgeries,A double blinded randomised study - Nil

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/11/077432

Enrollment

Registered

2024-11-27

Start date

Unknown

Completion date

Unknown

Last updated

2024-12-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Buprenorphine 0.5 mL with 2% lignocaine adrenaline 15ml and 5ml normal saline: Buprenorphine 0.5 mL with 2% lignocaine adrenaline 15 mL and normal saline 5ml in ultrasound guided poplit

Eligibility

Inclusion criteria

Inclusion criteria: Patients coming for below knee surgeries coming for both elective and emergency with American society of Anaesthesiologist(ASA) grade 1,grade 2,grade 3

Exclusion criteria

Exclusion criteria: Patient refusal Known allergy to local anesthetics Bleeding diathesis Use of any anti-coagulants Inability to provide informed consent Severe kidney or liver disease Patient with psychiatric disorders

Design outcomes

Primary

Measure	Time frame
To compare the duration of analgesiaTimepoint: First 24 hours	—

Secondary

Measure	Time frame
To compare the additional analgesic requirement in first 24 hoursTimepoint: First 24 hours	—

Countries

India

Contacts

Public ContactDr Vinith kumar

Chettinad Academy of Research and Education Chettinad Health City

dr_muruganand@yahoo.co.in9444486183

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026