The effect and safety of isobaric drugs ropivacaine and levobupivacaine for segmental spinal block in high risk patients undergoing abdominal surgery.

Efficacy and safety of isobaric ropivacaine and levobupivacaine for segmental spinal block in high risk patients undergoing abdominal surgery. A randomized controlled study. - NIL

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/11/077335

Enrollment

Registered

2024-11-25

Start date

Unknown

Completion date

Unknown

Last updated

2024-12-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Segmental spinal block (SSB): SSB will be given by experienced anaesthesiologistin sitting position with full aseptic precautions at T11- T12/ T12-L1 intervertebral space in midline app

Eligibility

Inclusion criteria

Inclusion criteria: Patients who will give consent to participate in the study

Exclusion criteria

Exclusion criteria: Patients with History of known hypersensitivity to study drugs Spinal deformity history of spine surgery

Design outcomes

Primary

Measure	Time frame
Sensory block characteristics • Time to achieve Sensory blockade at T6 dermatome (min) • Maximum height of sensory level achieved (min) • Time to achieve maximum sensory blockade (min) • Time-taken for 2 segment regression (min) 2. Motor block characteristics • Time to onset of motor blockade(BS3) • Time to reach Bromage score (BS0) 3. Haemodynamic variables • SBP/DBP (MAP) • Heart Rate(bpm) • SPO2 (%) Timepoint: 1) It will be measured in minutes for sensory and motor blockade 2) Haemodynamics will be measured infra operatively and post operatively for hours	—

Measure

Time frame

Sensory block characteristics • Time to achieve Sensory blockade at T6 dermatome (min) • Maximum height of sensory level achieved (min) • Time to achieve maximum sensory blockade (min) • Time-taken for 2 segment regression (min) 2. Motor block characteristics • Time to onset of motor blockade(BS3) • Time to reach Bromage score (BS0) 3. Haemodynamic variables • SBP/DBP (MAP) • Heart Rate(bpm) • SPO2 (%) Timepoint: 1) It will be measured in minutes for sensory and motor blockade 2) Haemodynamics will be measured infra operatively and post operatively for hours

—

Secondary

Measure	Time frame
To evaluate & compare the following parameters in between two groups 1. Postoperative analgesia in terms of a) Pain assessment using Visual Analogue Scale (VAS) b) Time to request for first rescue analgesia (TFA) 2. Intraoperative & postoperative adverse effects 3. Surgeon & patient satisfaction score Timepoint: It can take few hours to 1 week depends on the patient & adverse effects.	—

Countries

India

Contacts

Public ContactCharu Sharma

Geetanjali medical college and hospitall

partaniseema@yahoo.in9414162150

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026