Difference in the effects of sevoflurane and propofol on kidney functions in patients undergoing spine surgery

Comparison of effect of propofol versus sevoflurane on renal function in patients undergoing spine surgery - NIL

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/11/077289

Enrollment

Registered

2024-11-25

Start date

Unknown

Completion date

Unknown

Last updated

2024-12-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Maintenance of anaesthesia by - Sevoflurane Inhalational anaesthesia.: General anaesthesia will be induced with Inj.propofol 2mg/kg, Inj.Fenatnyl 2mcg/kg and Inj.rocuronium 0.6mg/kg and

Eligibility

Inclusion criteria

Inclusion criteria: ASA 1 and 2 Elective spine surgery

Exclusion criteria

Exclusion criteria: Allergic to Propofol and Sevoflurane Insulin treated Diabetes mellitus BMI more than 37/kg/meter square Kidney disease according to KDIGO criteria NYHA class 3 and 4

Design outcomes

Primary

Measure	Time frame
Urine outputTimepoint: 30 minutes into anesthesia 0-2 hours in the post operative period 24 hours after anesthesia	—

Secondary

Measure	Time frame
Kidney injury molecule Serum creatinine Creatinine clearence Serum electrolytesTimepoint: Preoperative 30 minutes into anesthesia 0-2 hours in the post operative period 24 hours post operative	—

Countries

India

Contacts

Public ContactDr Mahesh Vakamudi

Sri ramachandra institute of higher education and research

vakamudi@gmail.com9840022626

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026