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Salivary melatonin levels and periodontal disease

Effect of full mouth disinfection on salivary melatonin levels and tannerella forsythia in chronic periodontitis patients: a clinical, biochemical and microbiological study. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2024/11/077256
Enrollment
30
Registered
2024-11-25
Start date
Unknown
Completion date
Unknown
Last updated
2024-12-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: full mouth disinfection: Patients will receive full mouth disinfection after base line saliva sampling Control Intervention1: Nil: Nil

Sponsors

Cheppalli Naga Pranavi
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: For group A (healthy periodontium): Subjects with age group: 25-50 years both males and females. Individuals having 20 teeth or more. Systemically healthy participants. Intact periodontium with BOP less than 10% and PD less than or equal to 3mm without clinical attachment loss or radiographic sign of alveolar bone destruction. For group B (chronic periodontitis): Chronic periodontitis with CAL greater than or equal to 2 mm, PD greater than or equal to 5 mm and radiographic bone loss extending to the mid-third of the root or beyond.

Exclusion criteria

Exclusion criteria: Patients with any systemic diseases. Patients taking medication affecting periodontal health. Patients who have undergone periodontal therapy in the past 6 months. Pregnant and lactating women. Participants with xerostomia. Smokers and Tobacco users.

Design outcomes

Primary

MeasureTime frame
Salivary melatonin levels, tannerella forsythiaTimepoint: Baseline, 3 months

Secondary

MeasureTime frame
Clinical parameters plaque index, gingival index, probing pocket depth, clinical attachment level and bleeding on probingTimepoint: Baseline and 3 months

Countries

India

Contacts

Public ContactDr Cheppalli Naga Pranavi

Sri Rajiv Gandi College of Dental Sciences and Hospital

umeshyadalam@gmail.com9844269511

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026