None listed
Conditions
Interventions
Intervention1: measurement of serum and urinary NGAL: Preterm newborns admitted within 24 hours of birth
Control Intervention1: All newborns: Admitted within 24 hours of birth
Sponsors
Medical Research Unit MLN Medical College Prayagraj
Eligibility
Inclusion criteria
Inclusion criteria: o Neonates will be included consecutively only if informed consent will be given by their caregivers. o Neonates admitted within first day of life.
Exclusion criteria
Exclusion criteria: o Known renal or any other congenital anomalies, sepsis, metabolic disease, hyperbilirubinemia o Receiving diuretics and other drugs that can affect kidney in the first 48 hours of admission. o If they did not survive beyond the first three days of life o If mother of the newborn who had chronic kidney disease, hypertension, severe systemic disease, diabetes mellitus or some other chronic disease will be excluded from the research to eliminate the adverse impact of their illness on infant stress and kidney function.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To identify kidney injury in preterm newborns by estimating urinary NGAL levels.Timepoint: baseline | — |
Secondary
| Measure | Time frame |
|---|---|
| • Compare the efficacy of urinary NGAL levels vs serum creatinine and urine output levels in detecting AKI in preterm newborns. • To observe clinical outcomes of newborn at different values of NGAL levels. • To identify risk factors for acute kidney injury in preterm births. Timepoint: 2 YEARS | — |
Countries
India
Contacts
Public ContactANUBHA SHRIVASTAVA
MLN MEDICAL COLLEGE
Outcome results
None listed