The effect LASER light and painkiller on pain after root canal treatment

A Comparative Evaluation of The Effect of Low-Level LASER Therapy, LASER-Activated Irrigation and Preoperative Aceclofenac on Post Endodontic Pain After Single Visit Root Canal Treatment - A Randomized Controlled Trial. - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/11/077228

Enrollment

Registered

2024-11-22

Start date

Unknown

Completion date

Unknown

Last updated

2024-12-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: A00-B99- Certain infectious and parasitic diseases

Interventions

Intervention1: low level laser therapy: Patients receiving preoperative placebo tablet and low-level laser therapy. Intervention2: laser activated irrigation: Patients receiving preoperative placebo

Eligibility

Inclusion criteria

Inclusion criteria: 1. Healthy patients aged between 18-40 years. 2. Permanent mandibular premolars with complete root formation. 3. Permanent mandibular premolars with diagnosis of symptomatic irreversible pulpitis with symptomatic apical periodontitis. 4. Permanent mandibular premolars indicated for primary root canal treatment with Periapical Index Score (PAI) of 1 or 2.

Exclusion criteria

Exclusion criteria: 1. Patients who are medically compromised. 2. Patients who had taken antibiotics in last 1 month and non-steroidal anti-inflammatory drugs 24 hours prior to procedure. 3. Patients contraindicated for Aceclofenac, Lignocaine, use of apex locator and patients allergic to latex. 4. Pregnant and lactating women. 5. Adjacent carious teeth. 6. Immature teeth or teeth with root resorption. 7. Teeth with calcified canals. 8. Teeth with sinus opening or periapical radiolucency with PAI score of 3 or higher.

Design outcomes

Primary

Measure	Time frame
post operative painTimepoint: 6hrs, 24hrs, 48hrs, 72hrs	—

Secondary

Measure	Time frame
no. of analgesics takenTimepoint: 6hrs, 24hrs, 42hrs, 72hrs	—

Countries

India

Contacts

Public ContactDr Darshan Dakshindas

Government Dental College and Hospital, Nagpur

ddakshindas22@gmail.com9823286490

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026