A study to compare efficacy of Palash Kshar and Priyangu Kshar on blood clot.

Assessment of Palsh Kshar (Butea monosperma) and Priyangu Kshar (Callicarpa macrophylla) as Potential Anticoagulant and Thrombolytic Agents: Preclinical and Clinical Investigations.

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/11/077225

Enrollment

100

Registered

2024-11-22

Start date

Unknown

Completion date

Unknown

Last updated

2024-12-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: R791- Abnormal coagulation profile

Interventions

None listed

Eligibility

Inclusion criteria

Inclusion criteria: III. Lipid Profile- a. LDL : 100-110mg/dL. b. TG: 150-170 mg/dL c. Total Cholesterol: 150-170mg/dL. IV. IFG/FPG -110to125 mg/dL , IGT -140to199 mg/dL (After intaking 75 gm glucose reading taken after 2hrs) & HbA1c- 5.7 to less than 6.5 V. BP: Systolic120 to139 mmhg, Diastolic 80 to 89mmhg VI. C-reactive Protein :0.3 -1.0mg/Dl VII. Urine Protein range : more than 80mg/dL/24hrs VIII. PT- If not within the limit of 11-13 seconds, APTT- If not within the limit of 21-35 IX. Right from the randomly selected patient the having history of any one or all of the following smoking cigarette, alcohol, overweight/ obese eating unhealthy diet not getting enough physical activity having a first degree relative who developed heart disease in early age (female-under 65, male- under 55) VII. No history of grave diseases.

Exclusion criteria

Exclusion criteria: I. Subjects having age not less than 40 years and not more than 60 years. II. Lipid Profile • LDL – more than 100-110mg/dl. .• Triglyceride – more than 150-170 mg/dl • Total Cholesterol – more than. 150-170mg/day. III. History of chronic disease. IV. Under medication for any pathological condition. V. Not willing to be written consent.

Design outcomes

Primary

Measure	Time frame
Effectiveness of Palash Kshar and Priyangu Kshar will be evaluated by their effect on the LDL, TG, Total cholesterol, BP, CRP, Urine protein range, IFG, FPG, IGT, PT, APTT during the conditions where the Participant’s above said clinical parameters are moving towards higher range. Timepoint: 3months	—

Secondary

Measure	Time frame
Changes of Wellbeing parameters of persons having history of Smoking, Alcoholism, Obesity, Unhealthy diet, Low physical activity etc. based on the assessment through SHORT FORM -36 (SF-36).Timepoint: 3months	—

Countries

India

Contacts

Public ContactDr Fairy Jana

IPGAE & R at SVSP

atipgaer@gmail.com9874849650

Outcome results