Health Condition 1: A150- Tuberculosis of lung
Conditions
Interventions
Intervention1: Therapeutic dose of Vitamin D along with ATT: Supplemented with oral doses of vitamin D3- 50,000 IU once a week for 8 weeks along with conventional Anti Tubercular Therapy.
Control Inte
Sponsors
State Task force Punjab
Eligibility
Inclusion criteria
Inclusion criteria: Newly diagnosed microbiologically confirmed smear positive Pulmonary Tuberculosis with serum 25 hydroxy cholecalciferol levels less than 30 ng/ml
Exclusion criteria
Exclusion criteria: 1) Patient’s refusal 2) Pregnancy or lactation 3) Miliary TB 4) MDR TB 5) Old treated pulmonary TB 6) Hypersensitivity to Vitamin D supplements 7) A history of hypercalcemia, sarcoidosis, nephrolithiasis, hyperparathyroidism, seizures or cancer in the past. 8) Serum calcium above 10.5 mg/ml. 9) Current use of cytotoxic or immunosuppressive drug
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1) To compare the rate of sputum conversion between vitamin D supplementation group and control groupTimepoint: 1 year | — |
Secondary
| Measure | Time frame |
|---|---|
| 2) To evaluate the safety & tolerability profile of therapeutic dose of vitamin D in TB patientsTimepoint: 6 months | — |
Countries
India
Contacts
Public ContactDr Ayushi Singh
Punjab Institute of Medical Sciences
Outcome results
None listed