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Comparing the Effects of Dexmedetomidine and Nalbuphine with Levobupivacaine in Lower Limb Surgery

Comparative Study Of Dexmedetomidine With Nalbuphine As Adjuvant To Intrathecal Hyperbaric Levobupivacaine For Lower Limb Orthopedic Surgeries. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/11/077163
Enrollment
60
Registered
2024-11-21
Start date
Unknown
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M00-M99- Diseases of the musculoskeletal system and connective tissue

Interventions

Intervention1: spinal anesthesia: dexmedetomidine 0.2 ml+ levobupivacaine3ml dexmedetomidine dose- 3 to 5 µg,route-intrathecally,duration-0min,5min,10min levobupivacaine- dose- ranging from 7.5 mg

Sponsors

Teerthankar Mahaveer Medical Medical College and Research Centre
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patient giving written and informed consent for orthopedic surgeries. 2.American Society of Anesthesiologist (ASA) physical status I-II . 3.Age group of 18-60 years old.

Exclusion criteria

Exclusion criteria: 1.Patient with contraindication to spinal anesthesia. 2.Patient with allergy to the drugs used in study. 3.Polytrauma patients with other associated injuries 4.Anticipated duration of the surgery more than 180min. 5.Patient with Coagulopathic disorders 6.Pregnant patients

Design outcomes

Primary

MeasureTime frame
1.To compare the onset of sensory and motor block between both the groups. 2.To compare between two groups the duration of sensory and motor block at (T10) level. Timepoint: 5,10,15,30,45,1h,2h,4h,8h

Secondary

MeasureTime frame
1. To record and compare post operative pain by Visual Analogue Scale (VAS) for 24 hours between both the groups. 2. To compare time of first rescue analgesia requirement between both the groups. 3. To compare total analgesic consumption in 24 hr post operatively by the patient between both the groups. 5. To compare hemodynamic parameters of the patient between both the groups. 6.To compare any complications occurring to the patient between both the groups. Timepoint: 1,2,4,8,16,24

Countries

India

Contacts

Public ContactDr Yogesh Kumar Chhetty

Teerthanker Mahaveer Medical College

dr.yogesh.chhetty@gmail.com7008304116

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 7, 2026