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Potential diagnostic markers for patients with high blood sugar and tooth infection.

Correlation of HbA1C and Gingival Crevicular Fluid Levels of NLRP3 in Type 2 Diabetes Mellitus Patients with Pulp Necrosis and Symptomatic Apical Periodontitis - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2024/11/077149
Enrollment
60
Registered
2024-11-20
Start date
Unknown
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: E119- Type 2 diabetes mellitus without complications

Interventions

None listed

Sponsors

Pranay Kumar Singh
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patient with SAP in one molar tooth and Type 2 DM 2. Patients with SAP in one molar tooth and no systemic disease 3. Patients with no other systemic disease

Exclusion criteria

Exclusion criteria: 1. Pregnant or lactating patients 2. Patients with systemic disease other than Type 2 Diabetes Mellitus 3. Tooth with furcation involvement 4. Patients with uncontrolled diabetes Mellitus

Design outcomes

Primary

MeasureTime frame
Difference in the levels of NLRP3 in Gingival Crevicular Fluid in the Type 2 Diabetes Mellitus patients with SAP in comparison to systemically healthy patients with SAP Timepoint: One week after the oral prophylaxis.—

Secondary

MeasureTime frame
Difference in the levels of HbA1c in the Type 2 Diabetes Mellitus patients with SAP in comparison to systemically healthy patients with SAP.Timepoint: One week after the oral prophylaxis.—

Countries

India

Contacts

Public ContactDr Aakansha Puri

Manav Rachna Dental College

aakanshapuri.sds@mrei.ac.in9741164564

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 7, 2026