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To compare the hemodynamic changes between two induction agents used for intubation in ICU : Etomidate vs Propofol. A Randomised Control Study

A comparison of hemodynamic changes between Etomidate vs Propofol as induction agents during intubation in ICU A Randomised Control Study - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/11/077145
Enrollment
112
Registered
2024-11-20
Start date
Unknown
Completion date
Unknown
Last updated
2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: R69- Illness, unspecified

Interventions

Intervention1: ETOMIDATE: Hemodynamic comparison between Etomidate and Propofol as induction agents during intubation in ICU. Study to be conducted over one year. Control Intervention1: PROPOFOL: Haem

Sponsors

FORTIS ESCORTS HOSPITAL FARIDABAD
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Age more than 18 yrs of either sex admitted in ICU requiring endotracheal intubation

Exclusion criteria

Exclusion criteria: 1.Age less than 18yrs requiring endotracheal intubation 2. Post cardiac arrest patients 3. Contraindications to Propofol or Etomidate 4. Known pregnancy 5. Lack of equipoise

Design outcomes

Primary

MeasureTime frame
To study the effect of the two induction agents-propofol and etomidate on haemodynamic instability like cardiovascular collapse or respiratory failure in ICU subjects.Timepoint: Outcome observed at time interval of 1minute, 5 minutes, 15 minutes and 30 minutes.—

Secondary

MeasureTime frame
1.Ease of Intubation Score 2.Change in oxygenation status 3.Injury during intubation Timepoint: Immediately after intubation, within a time frame of 30 minutes.—

Countries

India

Contacts

Public ContactDR SURAVI SAMANTA

FORTIS ESCORTS HOSPITAL, FARIDABAD, HARYANA

dr.amandeepsingh@gmail.com9910052552

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 11, 2026