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A study of the significance of blood cells (their size , volume and distribution )in a patient suffering from Stroke and their effect on the severity of the stroke

A Study of Clinical significance of Platelet Indices in Acute Ischemic Stroke and its effect on clinical outcome- an Observational study - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2024/11/077138
Enrollment
133
Registered
2024-11-20
Start date
Unknown
Completion date
Unknown
Last updated
2024-12-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: G00-G99- Diseases of the nervous system

Interventions

None listed

Sponsors

DEPARTMENT OF GENERAL MEDICINE, KASTURBA MEDICAL COLLEGE, MANIPAL
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ANYBODY WHO IS ABOVE THE AGE OF 18 YEARS AND DIAGNOSIS OF ISCHEMIC STROKE CONFIRMED BY CRANIAL CT OR MRI WITHIN THE FIRST 24 HOURS OF THE DISEASE APPEARANCE

Exclusion criteria

Exclusion criteria: Hemorrhagic Stroke, Previous Stroke, TIA, Head Trauma, Previous Brain surgery , CNS Infection CKD CLD Post CABG HIV-AIDS Patients Autoimmune diseases / positive CRP/ Acute infection Anti-Platelet , Anti-lipids, ACE inhibitors, Anticoagulants, Hydroxyurea Anticancer drugs PVD Leukemia / Thrombocytopenia / Vit B12 deficiency/ MPS / ITP

Design outcomes

Primary

MeasureTime frame
To measure the Mean platelet Volume (MPV), Platelet Distribution Width (PDW) Plateletcrit (PCrt), Platelet-to-White Blood Cell Ratio (PWR) and Platelet to Lymphocyte ratio (PLR). To assess Verity of ischemic stroke by the National Institute of Health Stroke Scale (NIHSS) Analyze the association between MPV, PDW, PCrt, PWR and PLR with NIHSSTimepoint: PROSPECTIVE LONGITUDINAL STUDY

Secondary

MeasureTime frame
Analyze the effect of comorbid illnesses such as Diabetes, Hypertension, Dyslipidemia on Platelet indices in ischemic Stroke.Timepoint: PROSPECTIVE LONGITUDINAL STUDY

Countries

India

Contacts

Public ContactDR SHIVASHANKAR KN

KMC MANIPAL

shishamed@gmail.com9448623861

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026