Health Condition 1: K029- Dental caries, unspecified Health Condition 2: C00-C14- Malignant neoplasms of lip, oral cavity and pharynx
Conditions
Interventions
Intervention1: Biotene oral balance gel and toothpaste: It has lactoperoxidase, lysozyme, glucose oxidase and xylitol which are responsible for its anti bacterial activity and also makes it a salivar
Sponsors
DrAnam Alam
Eligibility
Inclusion criteria
Inclusion criteria: 1.With previous radiotherapy treatment where the field of irradiation encompasses the major and minor salivary glands. 2.With a subjective complaint of dry mouth. 3.With at least 10 remaining natural teeth and taking nutrition orally. 4.Participants should have finished radiotherapy 1 week prior to the study with a radiation dose more than 60Gy, present with skin integrity, have no history of neck dissection level I or any tumor lesion in the salivary glands. 5.Participants should report complaints compatible with xerostomia and hyposalivation, which will be later confirmed by sialometry.
Exclusion criteria
Exclusion criteria: 1.Patients with performing stimulated salivary flow rate (SSF) above 1mL/min. 2.Patients having severe dysphagia, or under hyposalivation treatment or salivary stimulants. 3.Patients whose radiation field did not include jaws, edentulous patients. 4.Those receiving a total radiotherapy dose of 50Gy or less.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Increase in the salivary flow, pH & buffering capacity & decrease in the caries susceptibilityTimepoint: Baseline 1 month 3 months 6 months | — |
Secondary
| Measure | Time frame |
|---|---|
| noneTimepoint: none | — |
Countries
India
Contacts
Public ContactDr Sonali Taneja
ITS-CDSR, Muradnagar
Outcome results
None listed