Comparison of effects of the Dexmedetomidine and Fentanyl as an adjuvant to Levobupivacaine in lower abdominal surgeries.

Comparison of the effects of Dexmedetomidine and Fentanyl as an adjuvant to 0.5% hyperbaric Levobupivacaine in lower abdominal surgeries :A randomized clinical trial. - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/11/077064

Enrollment

Registered

2024-11-19

Start date

Unknown

Completion date

Unknown

Last updated

2024-12-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Comparison of the effects of Dexmedetomidine and Fentanyl as an adjuvant to 0.5% hyperbaric Levobupivacaine in lower abdominal surgeries :A randomized clinical trial.: Spinal anaesthesi

Eligibility

Inclusion criteria

Inclusion criteria: AMERICAN SOCIETY OF ANAESTHESIOLOGIST(ASA) PHYSICAL STATUS CLASS 1 AND 2

Exclusion criteria

Exclusion criteria: 1. Patient’s refusal. 2. Patient having Bleeding disorders. 3. Patient having Neurological disease. 4. Patient having Local skin infections at the site of spinal block. 5. Patient having Severe back deformities. 6. Patient having Raised intracranial pressure. 7. Patient having Cardiac and respiratory disease. 8. Patient of Morbid obesity. 9. Patient having allergy to study drugs.

Design outcomes

Primary

Measure	Time frame
1.The onset of sensory block at T-10 level will be taken as the time from injection of anesthetic solution to the loss of sensation to pinprick. 2.Duration will be taken as from time of onset to time at which patient feel sensation to pinprick at T-10. 3.Onset time of motor block will be taken as the time to acquire complete motor block after the intrathecal injection of local anesthetic. 4.Total duration will be taken as time from onset to completely recover from the motor block.Timepoint: After the block, vitals will be monitored 2, 5, 10, 15, 20 and 30 min and thereafter, every 10 min interval till 90 minutes and 30 min intervals thereafter.	—

Measure

Time frame

1.The onset of sensory block at T-10 level will be taken as the time from injection of anesthetic solution to the loss of sensation to pinprick. 2.Duration will be taken as from time of onset to time at which patient feel sensation to pinprick at T-10. 3.Onset time of motor block will be taken as the time to acquire complete motor block after the intrathecal injection of local anesthetic. 4.Total duration will be taken as time from onset to completely recover from the motor block.Timepoint: After the block, vitals will be monitored 2, 5, 10, 15, 20 and 30 min and thereafter, every 10 min interval till 90 minutes and 30 min intervals thereafter.

—

Secondary

Measure	Time frame
HYPOTENSION BRADYCARDIA NAUSEA VOMITING SHIVERINGTimepoint: TOTAL DURATION WILL BE TAKEN AS TIME TO COMPLETELY RECOVER FROM THE BLOCK	—

Countries

India

Contacts

Public ContactDR Sheetal

Maharaja Agrasen Medical College,Agroha,District Hisar

sheetalbhatia1234@gmail.com8950426301

Outcome results