Health Condition 1: M968- Other intraoperative and postprocedural complications and disorders of musculoskeletal system, not elsewhere classified
Conditions
Interventions
Intervention1: Vancomycin Antibiotic solution during ACL graft preparation.: Graft is placed in vancomycin solution ( 500 mg of vancomycin powder in 100 mL normal saline) for 10mins to 15 mins during
Sponsors
Rajendra Institute of Medical Sciences
Eligibility
Inclusion criteria
Inclusion criteria: a) Individuals diagnosed with a complete rupture of the ACL who are indicated for surgical reconstruction b) patients willing to provide informed consent to participate in the study c) patients with no history of no prior ACL reconstruction surgery d) patients without significant comorbidities or medical conditions
Exclusion criteria
Exclusion criteria: a) patients with concurrent injuries involving multiple major ligaments of the knee b) patients younger than 18 years or older than 65 years c) patients with previous history of ACL reconstruction of the same knee d) patients with active systemic or local infection
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the infection rates in patients undergoing ACL reconstruction surgeryTimepoint: Postoperative day(POD)- 2,6,10 | — |
Secondary
| Measure | Time frame |
|---|---|
| a) To evaluate the incidence of graft failure(graft rupture or re-tear) between the two study groups b) to explore whether patients characteristics such as age, sex, BMI and previous medical history influence the clinical outcomes and infection rates in both study groupsTimepoint: 1 month and 3 months after surgery | — |
Countries
India
Contacts
Public ContactGovind Kumar Gupta
Rajendra Institute of Medical Sciences , Ranchi
Outcome results
None listed