A study to compare the effectiveness of two different volumes of Ropivacaine in a block for post operative pain relief in upper limb orthopaedic surgeries

Comparison of Ultrasound Guided Interscalene Brachial Plexus Block with 6ml and 10ml of 0.25 percent Ropivacaine for post operative analgesia in elective upper limb orthopaedic surgeries: A Randomised Controlled Trial - Nil

Status

Recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/11/077007

Enrollment

Registered

2024-11-19

Start date

Unknown

Completion date

Unknown

Last updated

2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Ultrasound Guided Interscalene Brachial Plexus Block: Injection Ropivacaine 0.25% 6ml Postoperatively before extubation. Time of completion of injection of local anaesthetic will be lab

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients posted for upper limb orthopaedic surgeries 2.Patients in ASA criteria 1,2 3.Patients with BMI less than 30 kg/m2

Exclusion criteria

Exclusion criteria: 1. History of allergy to study drug 2. Patient with coagulation disorders 3. Infection at site of block 4. Severe bronchopulmonary disease 5. Neurological deficit in the operating arm 6. Patient not willing to participate

Design outcomes

Primary

Measure	Time frame
To compare post operative analgesia between 6 ml of 0.25% Ropivacaine vs 10 ml of 0.25% Ropivacaine in ultrasound (USG) guided Interscalene brachial plexus block for Elective Upper Limb Orthopedic surgeriesTimepoint: 1. Total analgesic dose required in 24 hours after block. 2. Numerical rating scale (NRS) for pain assessment at 0.5, 1, 1.5, 2, 4, 6, 12, 24 hrs after block in first 24 hours. 3. Time for requirement for first rescue analgesia after block in first 24 hours.	—

Measure

Time frame

To compare post operative analgesia between 6 ml of 0.25% Ropivacaine vs 10 ml of 0.25% Ropivacaine in ultrasound (USG) guided Interscalene brachial plexus block for Elective Upper Limb Orthopedic surgeriesTimepoint: 1. Total analgesic dose required in 24 hours after block. 2. Numerical rating scale (NRS) for pain assessment at 0.5, 1, 1.5, 2, 4, 6, 12, 24 hrs after block in first 24 hours. 3. Time for requirement for first rescue analgesia after block in first 24 hours.

—

Secondary

Measure	Time frame
To compare side effects of 0.25 percent Ropivacaine 6 ml & 0.25 percent Ropivacaine 10 ml in Ultrasound guided Interscalene Block for Upper limb Orthopaedic surgeriesTimepoint: 1.Incidence of Hemi diaphragmatic paresis at 0.5 & 1 hrs after block 2.Hemodynamic stability at 0.5 & 1 hrs after block 3.Post operative Nausea & Vomiting Upto 24 hrs after block All to be assessed for first 24 hours	—

Countries

India

Contacts

Public ContactGayatri Awatade

N.K.P Salve Institute of Medical Sciences and Research Centre and Lata Mangeshkar Hospital

anjali_bhure@yahoo.co.in9822563121

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026