This study is to find out the beneficial action of vitamin A gel application over a wound caused by laser removal of white type of cancer patches in mouth.

A comparative study to evaluate the efficacy of vitamin A topical application in wound healing of laser ablation treatment in oral leukoplakia : A randomized control trial - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/11/076989

Enrollment

Registered

2024-11-19

Start date

Unknown

Completion date

Unknown

Last updated

2024-12-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K132- Leukoplakia and other disturbancesof oral epithelium, including tongue

Interventions

Intervention1: Laser ablation and vitamin A topical application group: Vitamin A application before 4 days of Laser ablation followed by 2 weeks of vitamin A topical application twice per day & routin

Eligibility

Inclusion criteria

Inclusion criteria: Homogenous leukoplakia histopathologically diagnosed

Exclusion criteria

Exclusion criteria: Patients with cardiac pacemaker Speckled and verrucous leukoplakia Pregnant and lactating mothers Extensive lesions(more than one anatomical site) Individuals Obese and under vitamin A supplements

Design outcomes

Primary

Measure	Time frame
Post operative pain Wound healingTimepoint: Day 2, 1st week,2nd week,3rd week, 4th week	—

Secondary

Measure	Time frame
Relapse RecurrenceTimepoint: 3rd and 6th month	—

Countries

India

Contacts

Public ContactDr S Ramasamy

Government Dental College and Hospital, Cuddalore

hod.omr.au@gmail.com9677522853

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026