Study Comparing Two Methods of Giving Spinal Anesthesia: One Full Dose vs fractioned Dose of 0.5% Heavy Bupivacaine for hip surgery in elderly patient

A randomised controlled trial to compare fractionated dose versus conventional bolus dose method of drug administration in spinal anaesthesia for surgical repair of hip fracture in the elderly patients - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/11/076978

Enrollment

Registered

2024-11-19

Start date

Unknown

Completion date

Unknown

Last updated

2024-12-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M849- Disorder of continuity of bone, unspecified

Interventions

Intervention1: Fractionated spinal anaesthesia versus conventional bolus dose of spinal anaesthesia: Patients are randomly selected Combined Spinal Epidural anaesthesia technique will be followed in b

Eligibility

Inclusion criteria

Inclusion criteria: Patients with American Society of Anaesthesiologists(ASA) physical status more than 2 BMI 18.5- 29.9

Exclusion criteria

Exclusion criteria: Patients refusal to participate in the study Patients with anatomical spinal deformities Patients with bleeding disorders and raised intracranial pressure Hypersensitivity to local anaesthetic and study drugs Local infection at site where needle for spinal is to be inserted Patients with dysthymia Patients on anticoagulant Failure of spinal anaesthesia

Design outcomes

Primary

Measure	Time frame
To assess hemodynamic changes following fractional and conventional bolus dose of 0.5% bupivacaine in spinal anaesthesia during spinal component of combined spinal epidural anaesthesiaTimepoint: At start of surgery, 3 minutes after start of surgery, 5 minutes after start of surgery then every 5 mins till end of surgery	—

Secondary

Measure	Time frame
1.Onset time of sensory(T10) level 2.Time taken for complete motor block 3.Two segment regression of sensory block 4.Duration of analgesia 5.Time of administration of first epidural bolus for anaesthesia 6.Total number of patients and doses of epidural bolus required in intraoperative period and in 24 hours 7.Any incidence of adverse effectTimepoint: At start of surgery, 3 minutes after start of surgery, 5 minutes after start of surgery then every 5 mins till end of surgery	—

Measure

Time frame

1.Onset time of sensory(T10) level 2.Time taken for complete motor block 3.Two segment regression of sensory block 4.Duration of analgesia 5.Time of administration of first epidural bolus for anaesthesia 6.Total number of patients and doses of epidural bolus required in intraoperative period and in 24 hours 7.Any incidence of adverse effectTimepoint: At start of surgery, 3 minutes after start of surgery, 5 minutes after start of surgery then every 5 mins till end of surgery

—

Countries

India

Contacts

Public ContactAkshay Kumar

Dr. Rajendra Prasad Government Medical College Tanda Kangra Himachal Pradesh

versha2u@yahoo.co.in9418152286

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026