Study comparing changes in hemodynamics and respiratory parameters in different modes of ventilation in patients undergoing spine surgeries in prone position.

The comparative study of effects of volume controlled ventilation (VCV) and pressure controlled ventilation (PCV) on hemodynamics and respiratory mechanics in patients undergoing spine surgeries in prone position-prospective randomised controlled study. - Nil

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/11/076960

Enrollment

Registered

2024-11-18

Start date

Unknown

Completion date

Unknown

Last updated

2024-12-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: PRESSURE CONTROLLED VENTILATION (PCV): All patients will be ventilated with Anesthesia workstation (Drager Atlan A350)P peak in PCV will be adjusted to deliver Vt of 8 ml/kg ideal body

Eligibility

Inclusion criteria

Inclusion criteria: ASA-1 and ASA-2 patients aged 20-60 years scheduled for elective spine surgeries in prone position under general anaesthesia will be enrolled for the study.

Exclusion criteria

Exclusion criteria: Body mass index (BMI) >30 Documented autonomic neuropathy Obstructive or restrictive lung diseases Repeat spine surgeries

Design outcomes

Primary

Measure	Time frame
To compare the effect of PCV with VCV on lung mechanics, oxygenation, ventilation and intra-operative bleeding.Timepoint: To compare the effects of respiratory mechanics after intubation under supine position, after proning, then at 20 minutes , 30 minutes, 60 minutes, 90 minutes, 120 mins , 150 minutes, 180 minutes, till the end of procedure	—

Secondary

Measure	Time frame
To evaluate the effect of these two modes of ventilation on hemodynamics.Timepoint: To study the hemodynamic changes I.e baseline & every 30 minutes.	—

Countries

India

Contacts

Public ContactDrAshwini H

Rajarajeswari medical college and hospital

drashwinih29@gmail.com8971265579

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026