To study the effect of aqueous extracts of amalaki on oxidative stress in subjects of metabolic syndrome associated with Ama

To study the effect of standardized aqueous extracts of Phyllanthus emblica fruits on the biomarker of oxidative stress in subjects with metabolic syndrome W.S.R. to Ama: A pilot study

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/11/076959

Enrollment

Registered

2024-11-18

Start date

Unknown

Completion date

Unknown

Last updated

2024-12-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: E70-E88- Metabolic disorders

Interventions

None listed

Eligibility

Inclusion criteria

Inclusion criteria: Patients having mandagni and having three or more following conditions present for enrollment (According to the NCEP ATP III definition, metabolic syndrome is present if three or more of the following five criteria are met): 1.waist circumference over 35 inches (men) or 31.5 inches (women), 2.blood pressure over 130/85 mmHg, 3.fasting triglyceride (TG) level over 150 mg/dl, 4.fasting high-density lipoprotein (HDL) 5.cholesterol level less than 40 mg/dl (men) or 50 mg/dl (women) fasting blood sugar over 100 mg/dl.

Exclusion criteria

Exclusion criteria: Individuals having Tikshna, vishama or samagni. Uncontrolled Hypertension & Hyperglycemia. Currently pregnant or post-partum state or lactating women. Cancer patients Cardiac Abnormalities (Cardiac Arrythmia, Congenital Heart Disease, Coronary Heart Disease, Heart Failure etc.) Any surgical intervention in the past 6 months

Design outcomes

Primary

Measure	Time frame
To study the effect of standardized aq. extract of phyllanthus embelica fruit on Ama dosha in subjects of Metabolic Syndrome.Timepoint: 12 weeks	—

Secondary

Measure	Time frame
1.To evaluate the effect of standardized aq. extract of phyllanthus embelica fruit on markers of oxidative stress(Nitric Oxide (NO), Glutathione (GSH) & Malondialdehyde (MDA) in subjects of metabolic syndrome. 2. To assess the quality of life of subjects through WHO-QOL BREF with the use of aq. extract of Phyllanthus EmbelicaTimepoint: 84 Days	—

Countries

India

Contacts

Public ContactDr Sujata Rajan

Ayurvedic and Unani Tibbia College and Hospital

sujataa.rajan@gmail.com9310811922

Outcome results