Health Condition 1: P09- Abnormal findings on neonatal screening
Conditions
Interventions
Intervention1: Intranasal Fentanyl and Oral Paracetamol: Oral Paracetamol:
The neonate will receive Oral Paracetamol Syrup (Paracet-S 5ml/125mg) at 15mg per kg of body weight, given 30 minutes before
Sponsors
AIIMS Jodhpur
Eligibility
Inclusion criteria
Inclusion criteria: All neonates admitted to the NICU fulfilling the criteria for ROP screening as per our unit protocol.
Exclusion criteria
Exclusion criteria: 1. Neonates who received Paracetamol or Fentanyl or any analgesics in the last 48 hours for pain control or sedation (Persistent pulmonary hypertension of the newborn) will be excluded. 2. Any malformation involving the nasal cavity, like choanal atresia, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain reduction will be measured using the PIPP-R score for the first 30 seconds after the ROP screening procedure.Timepoint: Immediately for 30 seconds after the ROP screening procedure | — |
Secondary
| Measure | Time frame |
|---|---|
| Compare the PIPP-R score in both groupsTimepoint: After speculum insertion and 2minutes, 5 minutes post ROP screening;To observe the increase or new onset of apnea, desaturation episodes, and their severity Timepoint: 48 hours following the ROP examination;To observe the occurrence of new-onset or exacerbation of feed intoleranceTimepoint: 48 hours following the procedure;To observe the heart rate patterns and Blood PressureTimepoint: Till 3 hours following the procedure;To evaluate the adverse effects profile of intranasal fentanylTimepoint: 48 hours post-administration.;To assess the cardiorespiratory stability scoreTimepoint: 48 hours post administration of intervention | — |
Countries
India
Contacts
Public ContactDr Sushil Kumar Choudhary
AIIMS Jodhpur
Outcome results
None listed