Health Condition 1: N888- Other specified noninflammatory disorders of cervix uteri
Conditions
Interventions
Control Intervention1: Ketamine and Dexmedetomidine: Patients will receive a loading dose of 1 mg/kg of ketamine and 1 µg/kg of dexmedetomidine over 3 mins followed by a maintenance infusion of dexmed
Sponsors
Dayanand Medical College and Hospital
Eligibility
Inclusion criteria
Inclusion criteria: American Society of Anaesthesiologists (ASA) grade I and II patients. Age group 18-65 years. Short obstetrics and gynaecological procedures(less than 30 minutes)
Exclusion criteria
Exclusion criteria: Patients allergic to the study drugs. Morbidly obese (BMI more than 40 kg/m2 ) Obstructive sleep apnoea. QTc prolongation more than 550 Ms. Second- or third-degree atrioventricular block. Opioid abuser. Patient refusal.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| comparison of time to first rescue bolus of ketamine between both the groups.Timepoint: Patient assessed every 3 minutes from start to the end of procedure for desired sedation and any procedural interference. Rescue bolus of ketamine will be given if there is any procedural interference or desired sedation is not achieved. Patient will be reevaluated ever 2 minutes | — |
Secondary
| Measure | Time frame |
|---|---|
| Total rescue dose of ketamine, awakening time, recovery time, surgeon satisfaction, recovery agitation, hemodynamic complications and adverse airway effects.Timepoint: Total time of the procedure and the time from the end of the procedure until achieving a modified Aldrete score = 9 | — |
Countries
India
Contacts
Public ContactDr Tanveer Singh
Dayanand Medical College and Hospital
Outcome results
None listed