Health Condition 1: I255- Ischemic cardiomyopathy
Conditions
Interventions
Intervention1: EECP & HBOT: Daily sessions of Hyperbaric oxygen therapy ( 20 x 90 minute sessions ) followed by 40 EECP sessions ( 1 hour each ) over a period of 6 weeks and follow up upto two years
C
Sponsors
Oxymed Hospital
Eligibility
Inclusion criteria
Inclusion criteria: Ischemic HFrEF( ejection fraction less than 50%) with NYHA Class 2 or more symptoms despite optimal GDMT. Post revascularization on GDMT with worsening heart failure symptoms. Coronary anatomy not suitable for repeat revascularization.
Exclusion criteria
Exclusion criteria: Recent acute coronary syndrome (within 1 month). Recent PTCA ( less than 2 weeks) or CABG (within 3 months). Severe peripheral arterial disease, greater than Moderate Aortic regurgitation or stenosis, HOCM, severe Mitral regurgitation, DVT , Arterial aneurysms, AFib with FVR , bleeding disorders, and uncontrolled hypertension. Volume overloaded pts
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| MACE First hospitalization due to heart failureTimepoint: 6 months 1 year 2 year | — |
Secondary
| Measure | Time frame |
|---|---|
| All cause mortality. Change from baseline in the clinical summary on the Minnesota living with heart failure score(MLFHS). Change from baseline of 6 minute walk distance. Change from baseline of Global longitudinal strain on 2D echocardiography. Change from baseline of NT pro BNP.Timepoint: 6 months 1 year 2 year | — |
Countries
India
Contacts
Public ContactDr Sama Akber DNB DM
Oxymed Hospital
Outcome results
None listed