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Study to evaluate the effect of Ayurveda medication; Brahmi Ghrita on memory loss.

Effect of Brahmi ghrita on cognitive, neurodegenerative and neurotrophic parameters in Mild Cognitive Impairment – A Double-blind Randomized Placebo-controlled Trial - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/11/076837
Enrollment
60
Registered
2024-11-14
Start date
Unknown
Completion date
Unknown
Last updated
2024-12-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: G300- Alzheimers disease with early onset

Interventions

None listed

Sponsors

Ministry of AYUSH, Government of India
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Subjects with Amnestic single or multi-domain mild cognitive impairment aged 55 years and above irrespective of gender. 2. Subjects with concern regarding a change in cognition, from the patient, an informant, or a skilled clinician. 3. Subjects with impairment in one or more cognitive domains relative to a person’s age and educational attainment. 4. Subjects who is independent in functional abilities (although they may take more time or be performed less efficiently)

Exclusion criteria

Exclusion criteria: 1. Patients with diagnosis of a major cognitive or neurodegenerative disorder. 2. Patients with history of head injury or CVA. 3. Patients diagnosed with severe mental disorders. 4. Patients with history of alcohol or substance abuse within the past 2 years. 5. Patients with uncontrolled diabetes, hypertension, dyslipidemia, or thyroid disease. 6. Patients with visual or hearing impairment impeding comprehension 7. Patients who are Participating in another intervention trial 8. Those who are undergoing treatment for mci under a professionally qualified ayurveda or yoga expert. 9. Those who are on regular herbal supplements for cognitive enhancement. 10. Those who are practicing yoga and meditation regularly in the last 6 months

Design outcomes

Primary

MeasureTime frame
Primary - Change in attention, Memory and executive functions (will be assessed using NIMHANS Neuropsychological battery for elderly ) Timepoint: Baseline (0th day) and after 12 weeks of intervention

Secondary

MeasureTime frame
Secondary - Plasma Neuro filament lite chain Serum BDNFTimepoint: Baseline (0th day) and after 12 weeks

Countries

India

Contacts

Public ContactDr Kishore Kumar R

National Institute of Mental Health and Neurosciences

ayurkishore@yahoo.com9845829174

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026