comparative study of poat operative pain using laser and N acetyle cystiene after endodontic therapy

Comparative evaluation of the effect of 970 nm diode laser with or without N acetyl cysteine on post operative pain after endodontic treatment in teeth with symptomatic apical periodontitis: a randomized clinical trial

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/11/076836

Enrollment

Registered

2024-11-14

Start date

Unknown

Completion date

Unknown

Last updated

2024-12-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K044- Acute apical periodontitis of pulpal origin

Interventions

Intervention1: 970NM diode LASER and N acetyl cystein: 970NM diode LSER irradiation carried out followed by N acetyl cystein intracanal medicament placed ,assesment of post operative pain at 8 hr , 2

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients with mandibular molar with symptomatic apical periodontitis 2. Periapical index up to 3 or 4. 3. Patient older than 18 to 60 years 4. Spontaneous pain 5. Percussion pain

Exclusion criteria

Exclusion criteria: • Periodontal probing greater than 3mm • Previous root canal treatment • Swelling / sinus tract • Sever periodontal disease • Antibiotic use within last 5 days • Systemic disorders • Pregnancy and lactation • Traumatic occlusion • Severe crown destruction preventing rubber dam isolation • Presence of other teeth requiring RCT

Design outcomes

Primary

Measure	Time frame
post operative pain assessment after root canal treatmentTimepoint: pre operative pain assessment post operative pain assessment at 8 hr after root canal treatment post operative pain assessment at24 hr after root canal treatment post operative pain assessment at48 hr after root canal treatment post operative pain assessment at72 hr after root canal treatment post operative pain assessment at 7DAY after root canal treatment	—

Measure

Time frame

post operative pain assessment after root canal treatmentTimepoint: pre operative pain assessment post operative pain assessment at 8 hr after root canal treatment post operative pain assessment at24 hr after root canal treatment post operative pain assessment at48 hr after root canal treatment post operative pain assessment at72 hr after root canal treatment post operative pain assessment at 7DAY after root canal treatment

—

Secondary

Measure	Time frame
post operative pain comparison among individuals of different age & genderTimepoint: preoperative pain , post operative pain 8hr , post operative pain 24hr , post operative pain 48 hr , post operative pain 72 hr post operative pain after 7 days after root canal treatment	—

Countries

India

Contacts

Public ContactJOE PAUL UMMBAVU

Bapuji Dental College and hospital

ncrashmi@yahoo.in7347228077

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026