A comparison of atracurium and cisatracurium on heart rate and blood pressure changes in patients undergoing laparoscopic surgeries.

A comparative study of efficacy of atracurium and cisatracurium for hemodynamic stability in patients undergoing laparoscopic surgeries - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/11/076818

Enrollment

Registered

2024-11-14

Start date

Unknown

Completion date

Unknown

Last updated

2024-12-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K87- Disorders of gallbladder, biliarytract and pancreas in diseases classified elsewhere Health Condition 2: K87- Disorders of gallbladder, biliarytract and pancreas in diseases classified elsewhere Health Condition 3: K92- Other diseases of digestive system

Interventions

Intervention1: Cisatracurium: Patients will be given Cisatracurium with initial dose of 0.15 mg/kg and maintainance dose of 0.03mg/kg. Heamodynamic Parameters will be monitored every 10 minutes till t

Eligibility

Inclusion criteria

Inclusion criteria: ASA GRADE 1 and 2 Patients undergoing elective laparoscopic surgeries

Exclusion criteria

Exclusion criteria: Patients with known hypersensitivity to neuromuscular blocking agents, BMI more than 30, patiets on beta blockers,patients on antipsychotics

Design outcomes

Primary

Measure	Time frame
To compare the hemodynamic parameters between cisatracurium and atracuriumTimepoint: 1 Baseline after the patient is shifted to Ot table 2 Immediately after administering NMBA 3 Immediately after Intubation 4 5 minutes after Intubation 5 Just before creation of pneumoperitoneum 6 Every 10 minutes till the completion of surgery 7 After desufflation 8 At extubation	—

Secondary

Measure	Time frame
To observe requirement of vasoactive agents inintraoperative period, complications like erythema, hypotension,bronchospam between the two groupsTimepoint: Baseline after the patient is shifted to Ot table Immediately after administering NMBA Immediately after Intubation 5 minutes after Intubation Just before creation of pneumoperitoneum Every 10 minutes till completion of surgery At the end of surgery At deflation At extubation	—

Measure

Time frame

To observe requirement of vasoactive agents inintraoperative period, complications like erythema, hypotension,bronchospam between the two groupsTimepoint: Baseline after the patient is shifted to Ot table Immediately after administering NMBA Immediately after Intubation 5 minutes after Intubation Just before creation of pneumoperitoneum Every 10 minutes till completion of surgery At the end of surgery At deflation At extubation

—

Countries

India

Contacts

Public ContactHarshada

Mgm Medical college and hospital Aurangabad

drsanhitakulkarni@gmail.com9881300645

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026