Health Condition 1: H186- Keratoconus
Conditions
Interventions
Intervention1: corneal collagen cross linking: all 3 groups undergo corneal collagen cross linking with different protocols with and without oxygen supplementation
Intervention2: Corneal Collagen Cros
Sponsors
PGIMER
Eligibility
Inclusion criteria
Inclusion criteria: 1)Age = 14 years 2)Thinnest pachymetry=375microns on pentacam 3)Kmax = 65D 4)Corrected distance visual acuity of less than 20/20on the snellen vison chart 5)Endothelial cell density > 200 cells/mm2 6)Abscense of any ocular surface disorders 7)patients who are willing to participate in the study
Exclusion criteria
Exclusion criteria: 1)presence of advanced cones 2) previous history of corneal surgery 3) history of herpetik keratitis 4)presence of any corneal guttate or other endothelial pathology 5)presence of autoimmune or connective tissue disease
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Demarcation line depth Best corrected visual acuity specular count change ultrastructural changes after procedure Timepoint: baseline,6 weeks and 12 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| change in keratocyte and subbasal corneal nerve density on IVCMTimepoint: at 6 weeks and at 3 months | — |
Countries
India
Contacts
Public ContactProf Chintan Malhotra
PGIMER
Outcome results
None listed