Health Condition 1: C320- Malignant neoplasm of glottis Health Condition 2: D141- Benign neoplasm of larynx
Conditions
Interventions
Intervention1: Dexmedetomidine group: 0.5 mcg/kg bolus of Dexmedetomidine will be administered over 10 minutes after induction followed by 0.5 mcg/kg/hr infusion which will be stopped 10 minutes befor
Sponsors
AIIMS New Delhi
Eligibility
Inclusion criteria
Inclusion criteria: Adult patients (18-75 years old) undergoing micro laryngeal surgeries (vocal cord polyp excision, biopsies, etc) under general anaesthesia.
Exclusion criteria
Exclusion criteria: ASA PS grade 3 and 4. Morbidly obese patients. Patients with pre existing vocal cord palsies. Patients with a pre operative heart rate less than 60 bpm. Patients planned for awake intubation. Pregnant women or lactating mothers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the incidence of grade 3 and 4 emergence cough between the two groups.Timepoint: Time period between the complete discontinuation of maintenance anaesthetic and 5 min after extubation. | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of emergence coughTimepoint: Time period between the complete discontinuation of maintenance anaesthetic and 5 min after extubation.;Time for extubationTimepoint: Time period between the complete discontinuation of maintenance anaesthetic to removing the breathing tube;Incidence of tachycardia/hypertension at extubationTimepoint: Time period between the complete discontinuation of maintenance anaesthetic and 5 min after extubation.;Time to achieve PADSS more than 9Timepoint: Time period from removing breathing tube to achieving PADSS more than 9 | — |
Countries
India
Contacts
Public Contactkelika prakash
All india Institute of Medical Sciences, New Delhi
Outcome results
None listed