Health Condition 1: J841- Other interstitial pulmonary diseases with fibrosis Health Condition 2: M958- Other specified acquired deformities of musculoskeletal system
Conditions
Interventions
Intervention1: nil: nil
Control Intervention1: nil: nil
Sponsors
Department of General Medicine
Eligibility
Inclusion criteria
Inclusion criteria: INCLUSION CRITERIA: 1. Patients who have a confirmed diagnosis of interstitial lung disease(ILD) associated with a known(CTD) connective tissue disease (e.g. rheumatoid arthritis, systemic sclerosis, dermatomyositis etc.). 2. Clinical Parameters: Individuals displaying relevant clinical symptoms such as cough, dyspnea (shortness of breath), fatigue, and evidence of lung involvement on imaging studies. 3. Confirmed Connective Tissue Disease: Patients diagnosed with a connective tissue disease with supportive evidence of Antibodies. 5. Patients Age ABOVE 18 years 6. diagnosed with any of the below mentioned connective tissue disorders: 1. Systemic Sclerosis 2. Systemic Lupus Erythematosus/SLE 3. Mixed Connective Tissue Disease (MCTD) 4. Rheumatoid Arthritis/RA 5. Inflammatory myositis- Dermatomyositis/Polymyositis 6. Sjogren’s disease 7. Undifferentiated Connective Tissue Disease (UCTD)
Exclusion criteria
Exclusion criteria: 1. Other Lung Diseases: Exclude individuals with lung diseases not associated with connective tissue disorders, such as chronic obstructive pulmonary disease (COPD) or pulmonary fibrosis unrelated to CTDs. 2. Drug-induced lung disease(like methotrexate induced) 3. Malignancy 4.Pregnant females 5. Active infections and comorbidities including congestive heart failure, renal and liver failure
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To Study the pattern of involvement of lung in various CTD-ILD (Connective Tissue Disease- related Interstitial Lung Disease)and IPAF (Interstitial pneumonia with autoimmune features) and to correlate the CTD(Connective Tissue Disease) pattern of ILD (Interstitial Lung Disease) with AUTOIMMUNE PROFILETimepoint: From the date of admission to date of discharge, and also follow-up during opd visits | — |
Secondary
| Measure | Time frame |
|---|---|
| To Assess the severity of the CTD-ILD (Connective Tissue- Interstitial Lung Disease) with the various markers including DLCO (Diffusing Capacity of the Lungs for Carbon Monoxide )/ RDW (red cell distribution width)/ CRP (C-Reactive Protein ) /NLR (neutrophil/lymphocyte ratio) To correlate CT pulmonary grading with DCLO (Diffusing Capacity of the Lungs for Carbon Monoxide )/PFT (Pulmonary Function Test)Timepoint: From the date of admission to date of discharge, and also follow-up during opd visits | — |
Countries
India
Contacts
Public ContactDr I Sri Hanuman
Kasturba Medical College , Manipal
Outcome results
None listed