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A clinical trial comparing the efficacy of PEEP ZEEP technique to conventional method of suctioning in reducing incidence of ventilator associated pneumonia in patients on invasive mechanical ventilation.

Efficacy in Reduction of Ventilator Associated Pneumonia in Patients with Invasive Mechanical Ventilation with PEEP ZEEP Technique Vs Conventional Method of Suctioning:A Randomised Controlled Study - NIL

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/11/076650
Enrollment
192
Registered
2024-11-12
Start date
Unknown
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J159- Unspecified bacterial pneumonia

Interventions

Intervention1: Method of Suctioning in patients on mechanical ventilation via PEEP ZEEP: Patient will be Ventilated with PEEP 15cm H2O,PIP 40 CM H2O for 1 min and Fio2-20% above baseline via Mindray

Sponsors

Heritage Institute of Medical Sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All age more than 18 years on controlled mechanical ventilation for more than 72 hours

Exclusion criteria

Exclusion criteria: Patient/Attendant refusal. Rib fracture ICD insitu Emphysematous bulla Pneumothorax Pleural Effusion Hemodynamic instability requiring noradrenaline more than 10 mcg/min PEEP requirement more than 12 cm H2O for SpO2 more than 92%. Severe bronchospasm(PIP-PPlat more than 20 cm H2O) . Severe Hypoalbuminemia (S.Albumin less than 2.5 g/dl) Ejection fraction less than 40%.

Design outcomes

Primary

MeasureTime frame
The PEEP-ZEEP technique has been proven to be a safe suction technique,which improves oxygenation without altering hemodynamics in intubated and mechanically ventilated patients. Compared to conventional suction technique it produces elevated expiratory flow that increases the movement of secretions towards the glottis.Hence, this elevated expiratory flow should decrease the incidence of Ventilator Associated Pneumonia in comparison to conventional method of suctioning. Timepoint: Baseline Samples will be collected before suctioning then,Immediately after then 20 mins post suctioning—

Secondary

MeasureTime frame
1)To study the effect of suctioning method on PaO2 and PaCo2 in patients on invasive mechanical ventilation. 2) To study the hemodynamic alterations due to suctioning by PEEP ZEEP technique Vs Conventional method in patients on invasive mechanical ventilationTimepoint: Immediately before initiation of suctioning, immediately after and 20 minutes post suctioning.—

Countries

India

Contacts

Public ContactDr Sulakshana

Heritage Institute of Medical Sciences,Varanasi

dr.sulakshanatripathi@gmail.com9389848829

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 7, 2026