To see agreement between 2 EEG based monitors between 2 anaesthetic techniques in abdominal surgeries

Evaluating correlation between Sedline and Entropy EEG based monitors on objective depth of Total Intravenous Anaesthesia (TIVA ) and Inhalational anaesthesia in abdominal surgeries: A prospective randomised trial - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/11/076648

Enrollment

Registered

2024-11-11

Start date

Unknown

Completion date

Unknown

Last updated

2024-12-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical Health Condition 2: O- Medical and Surgical

Interventions

Intervention1: Propofol Entropy (PE) group: Patients will receive intial IV propofol infusion dose at 50 µg/kg/min.The dose will be adjusted so as to maintain entropy in range 40 to 60 Intervention

Eligibility

Inclusion criteria

Inclusion criteria: ASA 1-2 Elective abdominal surgeries

Exclusion criteria

Exclusion criteria: 1.Neurologic disease 2.emergency/neurosurg/frontal sinus surgery 3. deformities/devices preventing application of EEG sensors to forehead 3. Patients having developmental delay 4.haemodynamic instability, Hypo/ Hyperthermia 5.Preoperative anxiety 6.receiving medications altering EEG 7.Surgery above 6 hrs duration

Design outcomes

Primary

Measure	Time frame
To assess the correlation agreement between Sedline and Entropy monitors during propofol TIVA and sevoflurane inhalational anaesthesiaTimepoint: Baseline, Induction [every 1 min for 5 min using the Modified Observers’ Assessment of Alertness/ Sedation (MOAAS) scale until the patient loses the eyelash reflex and achieves a score of 0], Intubation, peritoneum retraction, 30, 60, 90, 120 min post peritoneum retraction, closure, emergence (every min till MOASS score reaches 4) and extubation	—

Measure

Time frame

To assess the correlation agreement between Sedline and Entropy monitors during propofol TIVA and sevoflurane inhalational anaesthesiaTimepoint: Baseline, Induction [every 1 min for 5 min using the Modified Observers’ Assessment of Alertness/ Sedation (MOAAS) scale until the patient loses the eyelash reflex and achieves a score of 0], Intubation, peritoneum retraction, 30, 60, 90, 120 min post peritoneum retraction, closure, emergence (every min till MOASS score reaches 4) and extubation

—

Secondary

Measure	Time frame
1.MAP, HR 2.assess Correlation between propofol sedation and sedline 3.assess correlation between Sevoflurane sedation and Entropy 4.To assess correlation sevoflurane sedation and sedline 5. To assess correlation between propofol sedation and EntropyTimepoint: Baseline, Induction [every 1 min for 5 min using the Modified Observers’ Assessment of Alertness/ Sedation (MOAAS) scale until the patient loses the eyelash reflex and achieves a score of 0], Intubation, peritoneum retraction, 30, 60, 90, 120 min post peritoneum retraction, closure, emergence (every min till MOASS score reaches 4) and extubation (every 1 minute till 5 minutes)	—

Measure

Time frame

1.MAP, HR 2.assess Correlation between propofol sedation and sedline 3.assess correlation between Sevoflurane sedation and Entropy 4.To assess correlation sevoflurane sedation and sedline 5. To assess correlation between propofol sedation and EntropyTimepoint: Baseline, Induction [every 1 min for 5 min using the Modified Observers’ Assessment of Alertness/ Sedation (MOAAS) scale until the patient loses the eyelash reflex and achieves a score of 0], Intubation, peritoneum retraction, 30, 60, 90, 120 min post peritoneum retraction, closure, emergence (every min till MOASS score reaches 4) and extubation (every 1 minute till 5 minutes)

—

Countries

India

Contacts

Public ContactSingam Geetha

Nizams Institute of Medical Sciences Hyyderabad: Pincode: 500082

singamgeetha11@gmail.com09441043075

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026